Purpose : This study was to find out the effect of oral health and disability on the quality of living of senior citizens with physical disabilities in local communities, as well as how the variables are correlated with each other and how well they explain their causality. Method : The study included 117 senior citizens with physical disabilities in local communities. The questionnaire included questions on the general characteristics of the respondents. For testing, Oral health status assessment (OHAT), WHODAS 2.0, and quality of life (EQ-5D) were used. Additionally, Pearson's correlation and hierarchical multiple regression analysis were applied. Results : Oral health and disability showed statistically significant correlation with quality of living. The regression analysis indicated significant effect of oral health and disability on quality of living. Among the sub-factors of WHODAS 2.0, self-maintenance and socializing with others exerted the most significant effect. Conclusion : The findings indicate the significant effect of oral health and disability on the quality of living of senior citizens with physical disabilities. In the future, it is hoped that it will be used as a variety of occupational therapy interventions so that people with physical disabilities can maintain their swallowing function and physical health and lead an independent life.