Objective : This study was a meta-analysis of previous studies to examine the integration of related factors depression University students of Korea, and to determine the relative importance among the relevant factors based on it. Methods : 2000-2014 papers posted on the National Science and Technology Information Center (NDSL), Nurimedia (DBpia), Academic Research Information Service (RISS), Korea Research Information(KISS), provide the text of the Library of Congress were collected using the service. The Key words a ‘University Student', ‘Depression', ‘Depression Factors' was used. Used the Down & Black level, evidence-based checklist was developed by the research (1998) (checklist) had analyzed the selected document metadata to assess the quality. Results : 47-studies selected research groups are divided into five factors(self-esteem, suicidal ideation, positive thinking, stresses, Internet and smartphone addiction). Using meta-analysis, we analyzed the effect sizes, statistical heterogeneity and publication amenities. As a result, the self-esteem of the five factors were not found heterogeneity. Effect size is a self-esteem and suicidal ideation “large effect size”, positive thinking and stress“medium effect size”, internet and smart phone addiction“small effect size”. Conclusion : Self-esteem and suicidal ideation are among the factors associated with depression in University students of Korea was found that the most relevant. It identified the factors associated with depression in college students, and could utilized as basis for the prevention of depression.