Objective : The purpose of this study is to investigate the factors affecting occupational therapist's job stress through meta-analysis. Methods : In order to achieve the purpose of the study, 15 studies that examined job stress of occupational therapists were selected for analysis. The general characteristics of individual papers and the magnitude of the effect of related variables on job stress were calculated. The effect size of related variables on job stress and sub-factors (Fisher z) were calculated. Results : The results were found that the effect size on job stress was not significant in the variables of education level, salary and age. The largest effect size was found to be turnover intention (ES=1.161). There was no significant effect size in sub-factors of interpersonal conflict, organization system and insufficient job control. There was a significant effects in physical environment, lack of reward, job insecurity, job demand and occupational climate. Conclusion : The results of this study were suggested that an approach depending on sub-factors is needed to reduce job stress of occupational therapists. Satisfaction, burnout, and self-efficacy, which are psychological factors, are considered to be needed a program for psychological empowerment in order to reduce the job stress of the occupational therapist with a medium effect size according to individual sub-factors.