Objective : This study aims to find out the effects of chronic diseases in wage-earning disabled people on self-efficacy, disability acceptance, and job satisfaction. Methods : 1580 persons with disabilities in wage employment were extracted using the 6-dimensional data of the 2nd wave of the Employment Panel for Persons with Disabilities. The subjects' demographic characteristics, chronic diseases, self-efficacy, disability acceptance, and job satisfaction were investigated and analyzed. Data were analyzed using descriptive statistics, independent t-test, Pearson's correlation analysis, and replication analysis. Results : Self-efficacy, acceptance of disability, and job satisfaction according to chronic disease status of wage earners with disabilities were higher in the obesity disease group than the chronic disease group. There was a significant difference in job satisfaction in the two groups, and there was a positive correlation between perception of disability, self-efficacy, and job satisfaction in the chronic disease group, but no correlation between self-efficacy and job satisfaction. Effect of chronic disease and disability acceptance on job satisfaction had a 4% explanatory power, and it was confirmed that chronic disease(ß=.07) and disability awareness(ß=.16) were factors influencing job satisfaction of wage earners with disabilities. Conclusion : It is believed that continuous education and management are needed for the management of chronic diseases other than disabilities of wage-earning disabled people, and education for the prevention of chronic diseases is also needed.